In some cases, VCA IgM antibodies may be detectable for several months. However, unlike VCA IgG antibodies, they disappear within a few weeks. VCA IgM antibodies are also directed against the virus shell and usually appear at the same time as VCA IgG antibodies. This makes the avidity test useful for estimating how long the infection has lasted as well as determining if it’s a current or past infection. As the infection progresses, they start to develop and mature. ĭuring the early stages of an infection, VCA IgG antibodies are immature and don’t bind as strongly to EBV antigens. It measures how mature VCA IgG antibodies are by seeing how strongly they bind to EBV antigens. In some cases where a clear diagnosis can’t be made, the IgG avidity test may be used. This also means that, by themselves, they are unhelpful in determining if you have a current or past infection. This means they will always be detectable, even if you are not suffering from a current infection. Once they are made, VCA IgG antibodies will stay in your blood for life. These antibodies typically appear at the same time as infection symptoms. Viral capsid antigen (VCA) IgG antibodies are directed against the protein shell (capsid) of the virus. The type of antibodies that are detected in your blood helps your doctor determine if you have a current or past infection. Your immune system produces antibodies against different parts, or antigens, of EBV. Types of Epstein-Barr Tests EBV-Specific Antibody Tests If the initial result is negative and your doctor still suspects mono, he may ask you to repeat the test a week or so later. Within the first week of symptoms, the monospot test may give you a false-negative result. However, in most commercially-available tests, you will only need to give a small blood sample from a finger prick. For this test, you may also need to have your blood drawn. Monospot test is a more rapid test that can give you results within minutes. Results usually take a few days to come back. To test for EBV-specific antibodies, you will need to get your blood drawn. īecause the disease is most common in young adults between the ages of 15 and 24, your doctor may take your age into account when deciding whether to order the test. Symptoms of mono usually last 2 to 3 weeks, though certain symptoms such as fatigue and muscle pain may last longer. Your doctor will order an Epstein-Barr virus test if they suspect that you have mono. However, it can be reactivated by stress or a weakened immune system. Īfter your body successfully fights the virus, it remains dormant in your cells and doesn’t cause any symptoms. Ībout 70% of people tested will have antibodies indicative of past infections. īy revealing which types of antibodies you have, the test can determine if you have a current or a past infection. These antibodies circulate in your blood and can be detected with the EBV test. If you have the virus, your body will produce different types of antibodies to help combat the infection. It is also known as the Epstein-Barr virus antibody profile. The Epstein-Barr virus test is a blood test that determines if your body is producing antibodies and mounting an immune response against EBV. The infection is usually without symptoms in children. A plus sign next to the number “” means that the information is found within the full scientific study rather than the abstract.ĮBV is a virus that causes mononucleosis, also known as “kissing disease” in adolescents and adults. If you feel that any of our content is inaccurate, out-of-date, or otherwise questionable, please leave a comment or contact us at that each number in parentheses is a clickable link to peer-reviewed scientific studies. Our goal is to not have a single piece of inaccurate information on this website. They are continually monitored by our internal peer-review process and if we see anyone making material science errors, we don't let them write for us again. Our science team must pass long technical science tests, difficult logical reasoning and reading comprehension tests. Our science team is put through the strictest vetting process in the health industry and we often reject applicants who have written articles for many of the largest health websites that are deemed trustworthy. Our team comprises of trained MDs, PhDs, pharmacists, qualified scientists, and certified health and wellness specialists.Īll of our content is written by scientists and people with a strong science background. We are dedicated to providing the most scientifically valid, unbiased, and comprehensive information on any given topic. We believe that the most accurate information is found directly in the scientific source. SelfDecode has the strictest sourcing guidelines in the health industry and we almost exclusively link to medically peer-reviewed studies, usually on PubMed.
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